Links to Publications
Papers funded by the familial hematologic malignancies program as of 6/27/16:
1. Racevskis J, Wiernik PH, Kirshner ED, Raghavan V, Paietta E: Absence of hereditary p53 mutations in eight familial Hodgkin’s disease pedigrees. Leukemia 1995; 9:1966-9.
2. Ashigbi MY, Venkatraj U, Agarwal V, Bello J, Wiernik PH: Intracranial Hodgkin’s disease in two patients with familial Hodgkin’s disease. Med Pediatr Oncol 1997; 28:255-8.
3. Deshpande HA, Hu X, Marino P, Jan NA, Wiernik PH: Anticipation in familial plasma cell dyscrasias. Br J Haematol 1998; 103:696-703.
4. Makower D, Marino P, Frank M, Wiernik PH: Familial hairy cell leukemia. Leukemia & Lymphoma 1998; 29:193-197.
5. Novik Y, Marino P, Makower DF, Wiernik PH: Familial erythroleukemia: a distinct clinical and genetic type of familial leukemias. Leukemia & Lymphoma 1998; 30:395-401.
6. Horwitz M, Wiernik PH: Pseudoautosomal linkage of Hodgkin’s disease. Am J Hum Genet 1999; 65:1413-1422.
7. Wiernik PH, Hu X, Ratech H, Fineberg S, Etkind P, Walewski JA: Non-Hodgkin’s lymphoma in women with breast cancer. Cancer J 2000; 6:336-342.
8. Etkind P, Du J, Khan A, Pillitteri J, Wiernik PH: Mouse mammary tumor virus-like ENV gene sequences in human breast tumors and in a lymphoma of a breast cancer patient. Clin Cancer Res 2000; 6:1273-1278.
9. Wiernik PH, Wang SQ, Hu X-P, Marino P, Paietta E: Age of onset evidence for anticipation in familial non-Hodgkin’s lymphoma. Br J Haematol 2000; 108:72-79.
10. Colovic MD, Jankovic M, Wiernik PH: Hairy cell leukemia in first cousins and review of the literature. Eur J Haematol 2001; 67:185-8.8.
Xu Y, Wiernik PH: Systemic lupus erythematosis and B-cell hematologic neoplasm. Lupus 2001; 10:841-850.
11. Wiernik PH, Ashwin M, Hu X-P, Paietta E, Brown K: Anticipation in familial chronic lymphocytic leukaemia. Br J Haematol 2001; 113:407-414.
12. Etkind PR, Stewart AFR, Dorai T, Purcell DJ, Wiernik PH: Clonal isolation of different strains of mouse mammary tumor virus-like DNA sequences from both breast tumors and non-Hodgkin’s lymphomas of individual patients diagnosed with both malignancies. Clin Cancer Res 2004; 10:5656-5664.
13. Wiernik PH: Second neoplasms in patients with chronic lymphocytic leukemia. Curr Treat Options Oncol 5: 215-223, 2004.
14. Lynch HT, Watson P, Tarantolo S, Wiernik PH, Quinn-Laquer B, Bergsagel KI, Huiart L, Olopade OI, Sobol H, Sanger W, Hogg D, Weisenburger D: Phenotypic heterogeneity in multiple myeloma families. J Clin Oncol, 2005; 23:685-693.
15. Hall MJ, Li L, Wiernik PH, Olopade I: BRCA2 mutation and the risk of hematologic malignancy. Leuk Lymphoma 2006; 47:765-767.
15. Kunthur A, Wiernik PH, Dutcher JP: Renal parenchymal tumors and lymphoma in the same patient: A case series and review of the literature. Am J Hematol 2006; 81:271-280.
16. Alexandrescu DT, Garino A, Brown-Balem KA, Wiernik PH: Anticipation in families with Hodgkin’s and non-Hodgkin’s lymphoma in their pedigrees. Leuk Lymphoma 2006; 47:2115-2127.
17. Alexandrescu DT, Wiernik PH: The influence of parental age and gender on anticipation in familial B-cell malignancies. Med Oncol 2007; 24:55-62.
18. Etkind PR, Stewart AAF, Wiernik PH: Mouse mammary tumor virus (MMTV)-like DNA sequences in the breast tumors of father, mother and daughter. Infectious Ag Cancer 2008; 3:2.
19. Salipante SJ, Mealiffe ME, Wechsler J, Krem MM, Liu Y, Namkoong S, Bhagat G, Kirchhoff T, Offit K, Lynch H, Wiernik PH, Roshal M, McMaster M, Tucker M, Fromm JR, Goldin LR, Horwitz MS: Mutations in a gene encoding a midbody kelch protein in familial and sporadic classical Hodgkin lymphoma lead to binucleated cells. Proc Natl Acad Sci (USA) 2009; 106:14920-14925.
20. Dutcher JP, Mourad WF, Ennis RD: Integrating innovative therapeutic strategies into th management of renal cell carcinoma. Oncology 2012; 26: 526-30.
21. Dutcher JP: Recent developments in the treatment of renal cell carcinoma. Ther Adv Urol 2013; 5: 338-53.
22. Wiernik PH: Optimal therapy for adult patients with acute myeloid leukemia in first complete remission. Curr Tret Options Oncol 2014; 15: 171-86.
23. Wiernik PH: Inching toward cure of acute myeloid leukemia: a summary of the progress made in the last 50 years. Med Oncol 2014; 31: 136-49.
24. Gale RP, Wiernik PH, Lazarus HM: Should persons with acute myeloid leukemia have a transplant in first remission? Leukemia 2014; 28: 1649-52.
25. Freireich EJ, Wiernik PH, Steemsma DP: The leukemias: a half century of discovery. J Clin Oncol 2014; 31: 3463-9.
26. Wiernik PH: Familial leukemias. Curr Treat Options Oncol 2015; 16:8 doi: 10.1007/s11864-014-0323-3.
27. Dutcher JP, Wiernik PH: Renal cell carcinoma in patients with a personal or family history of hematologic malignancies. Clin Adv Hematol Oncol 2015; 13: 392- 397.
28. Wiernik PH, Wickramasinghe D, Dutcher JP: Families with both Hodgkin lymphoma and multiple myeloma in their pedigrees. Clin Adv Hematol Oncol 2015; 13: 257-260.
29. Wiernik PH: Alvocidib (flavopiridol) for the treatment of chronic lymphocytic leukemia. Expert Opin Investig Drugs 2016, 25: 729-34.
30. Dutcher JP, Fan W, Wiernik PH: Pure red cell aplasia following interleukin-2 therapy. J Investig Med High Impact Case Rep 2016; 4: 2324709616643991.
31. Dutcher JP, Wiernik PH, Varella L, Chintapatla R: Occurrence of renal cell carcinoma and hematologic malignancies (predominantly lymphoid) in individuals and in families. Fam Cancer 2016; in press. DOI 10.1007/s10689-016-9911-7